Statistical integration of multi-omics and drug screening data from cell lines
Statistical integration of multi-omics and drug screening data from cell lines
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Data integration methods are used to obtain a unified summary of multiple datasets. For multi-modal data, we propose a computational workflow to jointly analyze datasets from cell lines. The workflow comprises a novel probabilistic data integration method, named POPLS-DA, for multi-omics data. The workflow is motivated by a study on synucleinopathi...
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Full title
Statistical integration of multi-omics and drug screening data from cell lines
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TN_cdi_plos_journals_3069179594
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_3069179594
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ISSN
1553-7358,1553-734X
E-ISSN
1553-7358
DOI
10.1371/journal.pcbi.1011809