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Statistical integration of multi-omics and drug screening data from cell lines

Statistical integration of multi-omics and drug screening data from cell lines

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_3069179594

Statistical integration of multi-omics and drug screening data from cell lines

About this item

Full title

Statistical integration of multi-omics and drug screening data from cell lines

Publisher

United States: Public Library of Science

Journal title

PLoS computational biology, 2024-01, Vol.20 (1), p.e1011809-e1011809

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Data integration methods are used to obtain a unified summary of multiple datasets. For multi-modal data, we propose a computational workflow to jointly analyze datasets from cell lines. The workflow comprises a novel probabilistic data integration method, named POPLS-DA, for multi-omics data. The workflow is motivated by a study on synucleinopathi...

Alternative Titles

Full title

Statistical integration of multi-omics and drug screening data from cell lines

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_3069179594

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_3069179594

Other Identifiers

ISSN

1553-7358,1553-734X

E-ISSN

1553-7358

DOI

10.1371/journal.pcbi.1011809

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