Nuclear export is a limiting factor in eukaryotic mRNA metabolism
Nuclear export is a limiting factor in eukaryotic mRNA metabolism
About this item
Full title
Author / Creator
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
Subjects
More information
Scope and Contents
Contents
The eukaryotic mRNA life cycle includes transcription, nuclear mRNA export and degradation. To quantify all these processes simultaneously, we perform thiol-linked alkylation after metabolic labeling of RNA with 4-thiouridine (4sU), followed by sequencing of RNA (SLAM-seq) in the nuclear and cytosolic compartments of human cancer cells. We develop...
Alternative Titles
Full title
Nuclear export is a limiting factor in eukaryotic mRNA metabolism
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_3069179625
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_3069179625
Other Identifiers
ISSN
1553-7358,1553-734X
E-ISSN
1553-7358
DOI
10.1371/journal.pcbi.1012059
