Design and characterization of protective pan-ebolavirus and pan-filovirus bispecific antibodies
Design and characterization of protective pan-ebolavirus and pan-filovirus bispecific antibodies
About this item
Full title
Author / Creator
Wirchnianski, Ariel S , Nyakatura, Elisabeth K , Herbert, Andrew S , Kuehne, Ana I , Abbasi, Shawn A , Florez, Catalina , Storm, Nadia , McKay, Lindsay G A , Dailey, Leandrew , Kuang, Erin , Abelson, Dafna M , Wec, Anna Z , Chakraborti, Srinjoy , Holtsberg, Frederick W , Shulenin, Sergey , Bornholdt, Zachary A , Aman, M Javad , Honko, Anna N , Griffiths, Anthony , Dye, John M , Chandran, Kartik and Lai, Jonathan R
Publisher
United States: Public Library of Science
Journal title
Language
English
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Publication information
Publisher
United States: Public Library of Science
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More information
Scope and Contents
Contents
Monoclonal antibodies (mAbs) are an important class of antiviral therapeutics. MAbs are highly selective, well tolerated, and have long in vivo half-life as well as the capacity to induce immune-mediated virus clearance. Their activities can be further enhanced by integration of their variable fragments (Fvs) into bispecific antibodies (bsAbs), aff...
Alternative Titles
Full title
Design and characterization of protective pan-ebolavirus and pan-filovirus bispecific antibodies
Authors, Artists and Contributors
Author / Creator
Nyakatura, Elisabeth K
Herbert, Andrew S
Kuehne, Ana I
Abbasi, Shawn A
Florez, Catalina
Storm, Nadia
McKay, Lindsay G A
Dailey, Leandrew
Kuang, Erin
Abelson, Dafna M
Wec, Anna Z
Chakraborti, Srinjoy
Holtsberg, Frederick W
Shulenin, Sergey
Bornholdt, Zachary A
Aman, M Javad
Honko, Anna N
Griffiths, Anthony
Dye, John M
Chandran, Kartik
Lai, Jonathan R
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_3069183370
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_3069183370
Other Identifiers
ISSN
1553-7374,1553-7366
E-ISSN
1553-7374
DOI
10.1371/journal.ppat.1012134
