A novel Trichinella spiralis serine proteinase disrupted gut epithelial barrier and mediated larval...
A novel Trichinella spiralis serine proteinase disrupted gut epithelial barrier and mediated larval invasion through binding to RACK1 and activating MAPK/ERK1/2 pathway
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Gut epithelium is the first natural barrier against Trichinella spiralis larval invasion, but the mechanism by which larval penetration of gut epithelium is not completely elucidated. Previous studies showed that proteases secreted by T. spiralis intestinal infective larvae (IIL) degraded tight junctions (TJs) proteins of gut epithelium and mediate...
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Full title
A novel Trichinella spiralis serine proteinase disrupted gut epithelial barrier and mediated larval invasion through binding to RACK1 and activating MAPK/ERK1/2 pathway
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TN_cdi_plos_journals_3069183575
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_3069183575
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ISSN
1935-2735,1935-2727
E-ISSN
1935-2735
DOI
10.1371/journal.pntd.0011872
