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CD11c is not required by microglia to convey neuroprotection after prion infection

CD11c is not required by microglia to convey neuroprotection after prion infection

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_3069192147

CD11c is not required by microglia to convey neuroprotection after prion infection

About this item

Full title

CD11c is not required by microglia to convey neuroprotection after prion infection

Publisher

San Francisco: Public Library of Science

Journal title

PloS one, 2023-11, Vol.18 (11), p.e0293301-e0293301

Language

English

Formats

Publication information

Publisher

San Francisco: Public Library of Science

More information

Scope and Contents

Contents

Prion diseases are caused by the misfolding of a normal host protein that leads to gliosis, neuroinflammation, neurodegeneration, and death. Microglia have been shown to be critical for neuroprotection during prion infection of the central nervous system (CNS), and their presence extends survival in mice. How microglia impart these benefits to the...

Alternative Titles

Full title

CD11c is not required by microglia to convey neuroprotection after prion infection

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_3069192147

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_3069192147

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0293301

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