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NGF effects promote the maturation of rat pancreatic beta cells by regulating GLUT2 levels and distr...

NGF effects promote the maturation of rat pancreatic beta cells by regulating GLUT2 levels and distr...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_3069265400

NGF effects promote the maturation of rat pancreatic beta cells by regulating GLUT2 levels and distribution, and glucokinase activity

About this item

Full title

NGF effects promote the maturation of rat pancreatic beta cells by regulating GLUT2 levels and distribution, and glucokinase activity

Publisher

United States: Public Library of Science

Journal title

PloS one, 2024-06, Vol.19 (6), p.e0303934

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

The nerve growth factor (NGF) participates in cell survival and glucose-stimulated insulin secretion (GSIS) processes in rat adult beta cells. GSIS is a complex process in which metabolic events and ionic channel activity are finely coupled. GLUT2 and glucokinase (GK) play central roles in GSIS by regulating the rate of the glycolytic pathway. The...

Alternative Titles

Full title

NGF effects promote the maturation of rat pancreatic beta cells by regulating GLUT2 levels and distribution, and glucokinase activity

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_3069265400

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_3069265400

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0303934

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