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HIF3A gene disruption causes abnormal alveoli structure and early neonatal death

HIF3A gene disruption causes abnormal alveoli structure and early neonatal death

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_3069285028

HIF3A gene disruption causes abnormal alveoli structure and early neonatal death

About this item

Full title

HIF3A gene disruption causes abnormal alveoli structure and early neonatal death

Publisher

United States: Public Library of Science

Journal title

PloS one, 2024-05, Vol.19 (5), p.e0300751-e0300751

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Transcriptional response to changes in oxygen concentration is mainly controlled by hypoxia-inducible transcription factors (HIFs). Besides regulation of hypoxia-responsible gene expression, HIF-3α has recently been shown to be involved in lung development and in the metabolic process of fat tissue. However, the precise mechanism for such propertie...

Alternative Titles

Full title

HIF3A gene disruption causes abnormal alveoli structure and early neonatal death

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_3069285028

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_3069285028

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0300751

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