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Melatonin mitigates chemotherapy-induced small intestinal atrophy in rats and reduces cytotoxicity i...

Melatonin mitigates chemotherapy-induced small intestinal atrophy in rats and reduces cytotoxicity i...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_3100497979

Melatonin mitigates chemotherapy-induced small intestinal atrophy in rats and reduces cytotoxicity in murine intestinal organoids

About this item

Full title

Melatonin mitigates chemotherapy-induced small intestinal atrophy in rats and reduces cytotoxicity in murine intestinal organoids

Publisher

United States: Public Library of Science

Journal title

PloS one, 2024-09, Vol.19 (9), p.e0307414

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Cancer continues to pose a significant global health challenge, with gastrointestinal (GI) cancers among the most prevalent and deadly forms. These cancers often lead to high mortality rates and demand the use of potent cytotoxic chemotherapeutics. For example, 5-fluorouracil (5-FU) forms the backbone of chemotherapy regimens for various GI cancers...

Alternative Titles

Full title

Melatonin mitigates chemotherapy-induced small intestinal atrophy in rats and reduces cytotoxicity in murine intestinal organoids

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_3100497979

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_3100497979

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0307414

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