The SARS-CoV-2 ORF6 protein inhibits nuclear export of mRNA and spliceosomal U snRNA
The SARS-CoV-2 ORF6 protein inhibits nuclear export of mRNA and spliceosomal U snRNA
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of coronavirus disease 19 (COVID-19). SARS-CoV-2 infection suppresses host innate immunity and impairs cell viability. Among the viral proteins, ORF6 exhibits potent interferon (IFN) antagonistic activity and cellular toxicity. It also interacts with the RNA export...
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Full title
The SARS-CoV-2 ORF6 protein inhibits nuclear export of mRNA and spliceosomal U snRNA
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TN_cdi_plos_journals_3123014084
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_3123014084
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0312098
