Modifications to rhesus macaque TCR constant regions improve TCR cell surface expression
Modifications to rhesus macaque TCR constant regions improve TCR cell surface expression
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United States: Public Library of Science
Journal title
Language
English
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Publisher
United States: Public Library of Science
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Contents
T cell immunotherapy success is dependent on effective levels of antigen receptor expressed at the surface of engineered cells. Efforts to optimize surface expression in T cell receptor (TCR)-based therapeutic approaches include optimization of cellular engineering methods and coding sequences, and reducing the likelihood of exogenous TCR α and β c...
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Full title
Modifications to rhesus macaque TCR constant regions improve TCR cell surface expression
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TN_cdi_plos_journals_3153511175
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_3153511175
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0314751
