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Investigating the miRNA-mRNA interactome of human trabecular meshwork cells treated with TGF-β1 prov...

Investigating the miRNA-mRNA interactome of human trabecular meshwork cells treated with TGF-β1 prov...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_3161750741

Investigating the miRNA-mRNA interactome of human trabecular meshwork cells treated with TGF-β1 provides insights into the pathogenesis of pseudoexfoliation glaucoma

About this item

Full title

Investigating the miRNA-mRNA interactome of human trabecular meshwork cells treated with TGF-β1 provides insights into the pathogenesis of pseudoexfoliation glaucoma

Publisher

United States: Public Library of Science

Journal title

PloS one, 2025, Vol.20 (1), p.e0318125

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Pseudoexfoliation glaucoma is a severe form of secondary open angle glaucoma and is associated with activation of the TGF-β pathway by TGF-β1. MicroRNAs (miRNAs) are small non-coding RNA species that are involved in regulation of mRNA expression and translation. To investigate what glaucomatous changes occur in the trabecular meshwork and how these...

Alternative Titles

Full title

Investigating the miRNA-mRNA interactome of human trabecular meshwork cells treated with TGF-β1 provides insights into the pathogenesis of pseudoexfoliation glaucoma

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_3161750741

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_3161750741

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0318125

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