Trichostatin A suppresses hearing loss by reducing oxidative stress and inflammation in an Alport sy...
Trichostatin A suppresses hearing loss by reducing oxidative stress and inflammation in an Alport syndrome model
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Alport syndrome (AS) is a genetic disorder marked by mutations in type IV collagen, leading to kidney glomerular dysfunction. AS also involves the cochlea, causing late-onset progressive hearing loss. Currently, there are no therapeutic drugs to protect hearing from AS. HDAC inhibitors (HDACis) are chemical compounds that block the activity of hist...
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Full title
Trichostatin A suppresses hearing loss by reducing oxidative stress and inflammation in an Alport syndrome model
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TN_cdi_plos_journals_3163756603
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_3163756603
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0316033
