Mesenchymal Progenitor Self-Renewal Deficiency Leads to Age-Dependent Osteoporosis in Sca-1/Ly-6A Nu...
Mesenchymal Progenitor Self-Renewal Deficiency Leads to Age-Dependent Osteoporosis in Sca-1/Ly-6A Null Mice
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Contents
The cellular and molecular mechanisms that underlie age-dependent osteoporosis, the most common disease in the Western Hemisphere, are poorly understood in part due to the lack of appropriate animal models in which to study disease progression. Here, we present a model that shows many similarities to the human disease. Sca-1, well known for its exp...
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Full title
Mesenchymal Progenitor Self-Renewal Deficiency Leads to Age-Dependent Osteoporosis in Sca-1/Ly-6A Null Mice
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TN_cdi_pnas_primary_100_10_5840
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_100_10_5840
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1036475100