Translation Arrest of SecM Is Essential for the Basal and Regulated Expression of SecA
Translation Arrest of SecM Is Essential for the Basal and Regulated Expression of SecA
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
The SecM protein of Escherichia coli contains an arrest sequence ( F150XXXXWIXXXXGIRAGP166), which interacts with the ribosomal exit tunnel to halt translation elongation beyond Pro-166. This inhibition is reversed by active export of the nascent SecM chain. Here, we studied the physiological roles of SecM. Arrest-alleviating mutations in the arres...
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Full title
Translation Arrest of SecM Is Essential for the Basal and Regulated Expression of SecA
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Record Identifier
TN_cdi_pnas_primary_101_33_12330
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_101_33_12330
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0404907101
