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Correlation between Tumor Regression and T Cell Responses in Melanoma Patients Vaccinated with a MAG...

Correlation between Tumor Regression and T Cell Responses in Melanoma Patients Vaccinated with a MAG...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_101_suppl_2_14631

Correlation between Tumor Regression and T Cell Responses in Melanoma Patients Vaccinated with a MAGE Antigen

About this item

Full title

Correlation between Tumor Regression and T Cell Responses in Melanoma Patients Vaccinated with a MAGE Antigen

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2004-10, Vol.101 (Suppl 2), p.14631-14638

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

The cancer-germline gene MAGE-3 codes for tumor-specific antigens recognized on many tumors by T lymphocytes. A MAGE-3 antigen presented by HLA-A1 has been used in several vaccination trials on metastatic melanoma patients. Only a small minority of patients have shown evidence of tumor regression. Attempts to correlate the tumor rejections with the...

Alternative Titles

Full title

Correlation between Tumor Regression and T Cell Responses in Melanoma Patients Vaccinated with a MAGE Antigen

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pnas_primary_101_suppl_2_14631

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_101_suppl_2_14631

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.0405743101

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