Acute stress increases interstitial fluid amyloid-β via corticotropin-releasing factor and neuronal...
Acute stress increases interstitial fluid amyloid-β via corticotropin-releasing factor and neuronal activity
About this item
Full title
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Publisher
United States: National Academy of Sciences
Journal title
Language
English
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Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
Aggregation of the amyloid-β (Aβ) peptide in the extracellular space of the brain is critical in the pathogenesis of Alzheimer's disease. Aβ is produced by neurons and released into the brain interstitial fluid (ISF), a process regulated by synaptic activity. To determine whether behavioral stressors can regulate ISF Aβ levels, we assessed the effe...
Alternative Titles
Full title
Acute stress increases interstitial fluid amyloid-β via corticotropin-releasing factor and neuronal activity
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TN_cdi_pnas_primary_104_25_10673_fulltext
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_104_25_10673_fulltext
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0700148104
