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surface on the androgen receptor that allosterically regulates coactivator binding

surface on the androgen receptor that allosterically regulates coactivator binding

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_104_41_16074_fulltext

surface on the androgen receptor that allosterically regulates coactivator binding

About this item

Full title

surface on the androgen receptor that allosterically regulates coactivator binding

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2007-10, Vol.104 (41), p.16074-16079

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Current approaches to inhibit nuclear receptor (NR) activity target the hormone binding pocket but face limitations. We have proposed that inhibitors, which bind to nuclear receptor surfaces that mediate assembly of the receptor's binding partners, might overcome some of these limitations. The androgen receptor (AR) plays a central role in prostate...

Alternative Titles

Full title

surface on the androgen receptor that allosterically regulates coactivator binding

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pnas_primary_104_41_16074_fulltext

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_104_41_16074_fulltext

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.0708036104

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