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Plant cyclotides disrupt epithelial cells in the midgut of lepidopteran larvae

Plant cyclotides disrupt epithelial cells in the midgut of lepidopteran larvae

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_105_4_1221_fulltext

Plant cyclotides disrupt epithelial cells in the midgut of lepidopteran larvae

About this item

Full title

Plant cyclotides disrupt epithelial cells in the midgut of lepidopteran larvae

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2008-01, Vol.105 (4), p.1221-1225

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Several members of the Rubiaceae and Violaceae plant families produce a series of cyclotides or macrocyclic peptides of 28-37 aa with an embedded cystine knot. The cyclic peptide backbone together with the knotted and strongly braced structure confers exceptional chemical and biological stability that has attracted attention for potential pharmaceu...

Alternative Titles

Full title

Plant cyclotides disrupt epithelial cells in the midgut of lepidopteran larvae

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pnas_primary_105_4_1221_fulltext

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_105_4_1221_fulltext

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.0710338104

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