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Experimentally observed phenomena on cardiac energetics in heart failure emerge from simulations of...

Experimentally observed phenomena on cardiac energetics in heart failure emerge from simulations of...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_106_17_7143_fulltext

Experimentally observed phenomena on cardiac energetics in heart failure emerge from simulations of cardiac metabolism

About this item

Full title

Experimentally observed phenomena on cardiac energetics in heart failure emerge from simulations of cardiac metabolism

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2009-04, Vol.106 (17), p.7143-7148

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

The failing heart is hypothesized to suffer from energy supply inadequate for supporting normal cardiac function. We analyzed data from a canine left ventricular hypertrophy model to determine how the energy state evolves because of changes in key metabolic pools. Our findings--confirmed by in vivo ³¹P-magnetic resonance spectroscopy--indicate that...

Alternative Titles

Full title

Experimentally observed phenomena on cardiac energetics in heart failure emerge from simulations of cardiac metabolism

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pnas_primary_106_17_7143_fulltext

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_106_17_7143_fulltext

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.0812768106

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