Infectious tolerance via the consumption of essential amino acids and mTOR signaling
Infectious tolerance via the consumption of essential amino acids and mTOR signaling
About this item
Full title
Author / Creator
Publisher
United States: National Academy of Sciences
Journal title
Language
English
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Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
Infectious tolerance describes the process of CD4⁺ regulatory T cells (Tregs) converting naïve T cells to become additional Tregs. We show that antigen-specific Tregs induce, within skin grafts and dendritic cells, the expression of enzymes that consume at least 5 different essential amino acids (EAAs). T cells fail to proliferate in response to an...
Alternative Titles
Full title
Infectious tolerance via the consumption of essential amino acids and mTOR signaling
Authors, Artists and Contributors
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Record Identifier
TN_cdi_pnas_primary_106_29_12055_fulltext
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_106_29_12055_fulltext
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0903919106
