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Antagonism of microRNA-126 suppresses the effector function of TH2 cells and the development of alle...

Antagonism of microRNA-126 suppresses the effector function of TH2 cells and the development of alle...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_106_44_18704_fulltext

Antagonism of microRNA-126 suppresses the effector function of TH2 cells and the development of allergic airways disease

About this item

Full title

Antagonism of microRNA-126 suppresses the effector function of TH2 cells and the development of allergic airways disease

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2009-11, Vol.106 (44), p.18704-18709

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Allergic asthma is an inflammatory disease of the lung characterized by abnormal T helper-2 (TH2) lymphocyte responses to inhaled antigens. The molecular mechanisms leading to the generation of TH2 responses remain unclear, although toll-like receptors (TLRs) present on innate immune cells play a pivotal role in sensing molecular patterns and in pr...

Alternative Titles

Full title

Antagonism of microRNA-126 suppresses the effector function of TH2 cells and the development of allergic airways disease

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pnas_primary_106_44_18704_fulltext

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_106_44_18704_fulltext

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.0905063106

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