Design and construction of diverse mammalian prion strains
Design and construction of diverse mammalian prion strains
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
Prions are infectious proteins that encipher biological information within their conformations; variations in these conformations dictate different prion strains. Toward elucidating the molecular language of prion protein (PrP) conformations, we produced an array of recombinant PrP amyloids with varying conformational stabilities. In mice, the most...
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Full title
Design and construction of diverse mammalian prion strains
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TN_cdi_pnas_primary_106_48_20417
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_106_48_20417
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0910350106
