Astrocyte elevated gene-1 (AEG-1) functions as an oncogene and regulates angiogenesis
Astrocyte elevated gene-1 (AEG-1) functions as an oncogene and regulates angiogenesis
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Publisher
United States: National Academy of Sciences
Journal title
Language
English
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Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
Astrocyte-elevated gene-1 (AEG-1) expression is increased in multiple cancers and plays a central role in Ha-ras-mediated oncogenesis through the phosphatidylinositol 3-kinase (PI3K)/Akt signaling pathway. Additionally, overexpression of AEG-1 protects primary and transformed human and rat cells from serum starvation-induced apoptosis through activ...
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Full title
Astrocyte elevated gene-1 (AEG-1) functions as an oncogene and regulates angiogenesis
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Record Identifier
TN_cdi_pnas_primary_106_50_21300
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_106_50_21300
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0910936106
