Inhibition of Mac-1 (CD11b/CD18) enhances tumor response to radiation by reducing myeloid cell recru...
Inhibition of Mac-1 (CD11b/CD18) enhances tumor response to radiation by reducing myeloid cell recruitment
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Despite recent advances in radiotherapy, loco-regional failures are still the leading cause of death in many cancer patients. We have previously reported that bone marrow-derived CD11b⁺ myeloid cells are recruited to tumors grown in irradiated tissues, thereby restoring the vasculature and tumor growth. In this study, we examined whether neutralizi...
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Inhibition of Mac-1 (CD11b/CD18) enhances tumor response to radiation by reducing myeloid cell recruitment
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TN_cdi_pnas_primary_107_18_8363
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_107_18_8363
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0911378107