Human serum protein enhances HIV-1 replication and up-regulates the transcription factor AP-1
Human serum protein enhances HIV-1 replication and up-regulates the transcription factor AP-1
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Author / Creator
Publisher
United States: National Academy of Sciences
Journal title
Language
English
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Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
In vitro studies on HIV (HIV-1) replication and neutralization are usually performed in human cell cultures supplemented with FBS instead of human serum (HS). Here we show that in contrast to FBS, addition of increasing amounts of human serum from noninfected donors to the cell culture directly correlates with an increase in HIV-1 replication in vi...
Alternative Titles
Full title
Human serum protein enhances HIV-1 replication and up-regulates the transcription factor AP-1
Authors, Artists and Contributors
Author / Creator
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Record Identifier
TN_cdi_pnas_primary_109_43_17639
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_109_43_17639
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1206893109
