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CDX1 confers intestinal phenotype on gastric epithelial cells via induction of stemness-associated r...

CDX1 confers intestinal phenotype on gastric epithelial cells via induction of stemness-associated r...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_109_50_20584

CDX1 confers intestinal phenotype on gastric epithelial cells via induction of stemness-associated reprogramming factors SALL4 and KLF5

About this item

Full title

CDX1 confers intestinal phenotype on gastric epithelial cells via induction of stemness-associated reprogramming factors SALL4 and KLF5

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2012-12, Vol.109 (50), p.20584-20589

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Intestinal metaplasia of the stomach, a mucosal change characterized by the conversion of gastric epithelium into an intestinal phenotype, is a precancerous lesion from which intestinal-type gastric adenocarcinoma arises. Chronic infection with Helicobacter pylori is a major cause of gastric intestinal metaplasia, and aberrant induction by H. pylor...

Alternative Titles

Full title

CDX1 confers intestinal phenotype on gastric epithelial cells via induction of stemness-associated reprogramming factors SALL4 and KLF5

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pnas_primary_109_50_20584

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_109_50_20584

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1208651109

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