Class III PI3K Vps34 plays an essential role in autophagy and in heart and liver function
Class III PI3K Vps34 plays an essential role in autophagy and in heart and liver function
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
A critical regulator of autophagy is the Class III PI3K Vps34 (also called PIK3C3). Although Vps34 is known to play an essential role in autophagy in yeast, its role in mammals remains elusive. To elucidate the physiological function of Vps34 and to determine its precise role in autophagy, we have generated Vps34f/f mice, in which expression of Cre...
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Full title
Class III PI3K Vps34 plays an essential role in autophagy and in heart and liver function
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TN_cdi_pnas_primary_109_6_2003
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_109_6_2003
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1112848109
