Role for the kinase SGK1 in stress, depression, and glucocorticoid effects on hippocampal neurogenes...
Role for the kinase SGK1 in stress, depression, and glucocorticoid effects on hippocampal neurogenesis
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Publisher
Washington, DC: National Academy of Sciences
Journal title
Language
English
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Publisher
Washington, DC: National Academy of Sciences
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Scope and Contents
Contents
Stress and glucocorticoid hormones regulate hippocampal neurogenesis, but the molecular mechanisms mediating these effects are poorly understood. Here we identify the glucocorticoid receptor (GR) target gene, serum- and glucocorticoid-inducible kinase 1 (SGK1), as one such mechanism. Using a human hippocampal progenitor cell line, we found that a s...
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Full title
Role for the kinase SGK1 in stress, depression, and glucocorticoid effects on hippocampal neurogenesis
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TN_cdi_pnas_primary_110_21_8708
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_110_21_8708
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1300886110
