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Activation-induced cytidine deaminase (AID) is necessary for the epithelial–mesenchymal transition i...

Activation-induced cytidine deaminase (AID) is necessary for the epithelial–mesenchymal transition i...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_110_32_E2977

Activation-induced cytidine deaminase (AID) is necessary for the epithelial–mesenchymal transition in mammary epithelial cells

About this item

Full title

Activation-induced cytidine deaminase (AID) is necessary for the epithelial–mesenchymal transition in mammary epithelial cells

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2013-08, Vol.110 (32), p.E2977-E2986

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Activation-induced cytidine deaminase (AID), which functions in antibody diversification, is also expressed in a variety of germ and somatic cells. Evidence that AID promotes DNA demethylation in epigenetic reprogramming phenomena, and that it is induced by inflammatory signals, led us to investigate its role in the epithelial–mesenchymal transitio...

Alternative Titles

Full title

Activation-induced cytidine deaminase (AID) is necessary for the epithelial–mesenchymal transition in mammary epithelial cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pnas_primary_110_32_E2977

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_110_32_E2977

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1301021110

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