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Vaccinia virus-mediated melanin production allows MR and optoacoustic deep tissue imaging and laser-...

Vaccinia virus-mediated melanin production allows MR and optoacoustic deep tissue imaging and laser-...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_110_9_3316

Vaccinia virus-mediated melanin production allows MR and optoacoustic deep tissue imaging and laser-induced thermotherapy of cancer

About this item

Full title

Vaccinia virus-mediated melanin production allows MR and optoacoustic deep tissue imaging and laser-induced thermotherapy of cancer

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2013-02, Vol.110 (9), p.3316-3320

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

We reported earlier the delivery of antiangiogenic single chain antibodies by using oncolytic vaccinia virus strains to enhance their therapeutic efficacy. Here, we provide evidence that gene-evoked production of melanin can be used as a therapeutic and diagnostic mediator, as exemplified by insertion of only one or two genes into the genome of an...

Alternative Titles

Full title

Vaccinia virus-mediated melanin production allows MR and optoacoustic deep tissue imaging and laser-induced thermotherapy of cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pnas_primary_110_9_3316

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_110_9_3316

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1216916110

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