Arginine starvation-associated atypical cellular death involves mitochondrial dysfunction, nuclear D...
Arginine starvation-associated atypical cellular death involves mitochondrial dysfunction, nuclear DNA leakage, and chromatin autophagy
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
Significance Nutritional starvation therapy is under intensive investigation because it provides a potentially lower toxicity with higher specificity than conventional cancer therapy. Autophagy, often triggered by starvation, represents an energy-saving, pro-survival cellular function; however, dysregulated autophagy could also lead to cell death,...
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Full title
Arginine starvation-associated atypical cellular death involves mitochondrial dysfunction, nuclear DNA leakage, and chromatin autophagy
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TN_cdi_pnas_primary_111_39_14147
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_111_39_14147
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1404171111