Circadian control of innate immunity in macrophages by miR-155 targeting Bmal1
Circadian control of innate immunity in macrophages by miR-155 targeting Bmal1
About this item
Full title
Author / Creator
Curtis, Anne M. , Fagundes, Caio T. , Yang, Guangrui , Palsson-McDermott, Eva M. , Wochal, Paulina , McGettrick, Anne F. , Foley, Niamh H. , Early, James O. , Chen, Lihong , Zhang, Hanrui , Xue, Chenyi , Geiger, Sarah S. , Hokamp, Karsten , Reilly, Muredach P. , Coogan, Andrew N. , Vigorito, Elena , FitzGerald, Garret A. and O’Neill, Luke A. J.
Publisher
United States: National Academy of Sciences
Journal title
Language
English
Formats
Publication information
Publisher
United States: National Academy of Sciences
Subjects
More information
Scope and Contents
Contents
Significance The circadian clock allows an organism to anticipate daily changes imposed by the environment. The response to LPS is altered depending on time of day; however, the molecular mechanisms underlying this are unclear. We find that the clock in myeloid cells plays a role in LPS-induced sepsis by altering NF-κB activity and the induction of...
Alternative Titles
Full title
Circadian control of innate immunity in macrophages by miR-155 targeting Bmal1
Authors, Artists and Contributors
Author / Creator
Fagundes, Caio T.
Yang, Guangrui
Palsson-McDermott, Eva M.
Wochal, Paulina
McGettrick, Anne F.
Foley, Niamh H.
Early, James O.
Chen, Lihong
Zhang, Hanrui
Xue, Chenyi
Geiger, Sarah S.
Hokamp, Karsten
Reilly, Muredach P.
Coogan, Andrew N.
Vigorito, Elena
FitzGerald, Garret A.
O’Neill, Luke A. J.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pnas_primary_112_23_7231
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_112_23_7231
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1501327112
