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Optogenetic determination of the myocardial requirements for extrasystoles by cell type-specific tar...

Optogenetic determination of the myocardial requirements for extrasystoles by cell type-specific tar...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_112_32_E4495

Optogenetic determination of the myocardial requirements for extrasystoles by cell type-specific targeting of ChannelRhodopsin-2

About this item

Full title

Optogenetic determination of the myocardial requirements for extrasystoles by cell type-specific targeting of ChannelRhodopsin-2

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2015-08, Vol.112 (32), p.E4495-E4504

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Extrasystoles lead to several consequences, ranging from uneventful palpitations to lethal ventricular arrhythmias, in the presence of pathologies, such as myocardial ischemia. The role of working versus conducting cardiomyocytes, as well as the tissue requirements (minimal cell number) for the generation of extrasystoles, and the properties leadin...

Alternative Titles

Full title

Optogenetic determination of the myocardial requirements for extrasystoles by cell type-specific targeting of ChannelRhodopsin-2

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pnas_primary_112_32_E4495

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_112_32_E4495

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1509380112

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