Caspase 3 cleavage of Pax7 inhibits self-renewal of satellite cells
Caspase 3 cleavage of Pax7 inhibits self-renewal of satellite cells
About this item
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Publisher
United States: National Academy of Sciences
Journal title
Language
English
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Publication information
Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
Compensatory growth and regeneration of skeletal muscle is dependent on the resident stem cell population, satellite cells (SCs). Self-renewal and maintenance of the SC niche is coordinated by the paired-box transcription factor Pax7, and yet continued expression of this protein inhibits the myoblast differentiation program. As such, the reduction...
Alternative Titles
Full title
Caspase 3 cleavage of Pax7 inhibits self-renewal of satellite cells
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Record Identifier
TN_cdi_pnas_primary_112_38_E5246
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_112_38_E5246
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1512869112
