HLA-DRB111 and variants of the MHC class II locus are strong risk factors for systemic juvenile idio...
HLA-DRB111 and variants of the MHC class II locus are strong risk factors for systemic juvenile idiopathic arthritis
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Author / Creator
Ombrello, Michael J. , Remmers, Elaine F. , Tachmazidou, Ioanna , Grom, Alexei , Foell, Dirk , Haas, Johannes-Peter , Martini, Alberto , Gattorno, Marco , Özen, Seza , Prahalad, Sampath , Zeft, Andrew S. , Bohnsack, John F. , Mellins, Elizabeth D. , Ilowite, Norman T. , Russo, Ricardo , Len, Claudio , Hilario, Maria Odete E. , Oliveira, Sheila , Yeung, Rae S. M. , Rosenberg, Alan , Wedderburn, Lucy R. , Anton, Jordi , Schwarz, Tobias , Hinks, Anne , Bilginer, Yelda , Park, Jane , Cobb, Joanna , Satorius, Colleen L. , Han, Buhm , Baskin, Elizabeth , Signa, Sara , Duerr, Richard H. , Achkar, J. P. , Kamboh, M. Ilyas , Kaufman, Kenneth M. , Kottyan, Leah C. , Pinto, Dalila , Scherer, Stephen W. , Alarcón-Riquelme, Marta E. , Docampo, Elisa , Estivill, Xavier , Gül, Ahmet , de Bakker, Paul I. W. , Raychaudhuri, Soumya , Langefeld, Carl D. , Thompson, Susan , Zeggini, Eleftheria , Thomson, Wendy , Kastner, Daniel L. , Woo, Patricia , Achkar, J. P. , Alarcón-Riquelme, Marta E. , Allen, Roger , Anton, Jordi , Baskin, Elizabeth , Berg, Stefan , Bica, Bianca , Bilginer, Yelda , Bohnsack, John F. , Cavalcanti, Andre , Chaitow, Jeffrey , Cobb, Joanna , Cuttica, Rubin , de Bakker, Paul I. W. , Docampo, Elisa , Duerr, Richard , Ellis, Justine , Estivill, Xavier , Finkel, Terri H. , Foell, Dirk , Gattorno, Marco , Grom, Alexei , Gül, Ahmet , Haas, Johannes-Peter , Hakonarson, Hakon , Han, Buhm , Hilario, Maria Odete E. , Hinks, Anne , Ilowite, Norman T. , Kamboh, M. Ilyas , Kaufman, Kenneth , Kottyan, Leah C. , Langefeld, Carl , Len, Claudio , Martini, Alberto , Mellins, Elizabeth D. , Minden, Kirstin , Murray, Kevin , Oliveira, Sheila , Ombrello, Michael J. , Ozen, Seza , Park, Jane , Pinto, Dalila , Prahalad, Sampath , Quartier, Pierre , Raychaudhuri, Soumya , Rosenberg, Alan , Russo, Ricardo , Satorius, Colleen , Scherer, Stephen W. , Childhood Arthritis Prospective Study (CAPS) Group , British Society of Pediatric and Adolescent Rheumatology (BSPAR) Study Group , Randomized Placebo Phase Study of Rilonacept in sJIA (RAPPORT) Investigators , the International Childhood Arthritis Genetics (INCHARGE) Consortium , Sparks-Childhood Arthritis Response to Medication Study (CHARMS) Group , Biologically Based Outcome Predictors in JIA (BBOP) Group and International Childhood Arthritis Genetics (INCHARGE) Consortium
Publisher
United States: National Acad Sciences
Journal title
Language
English
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Publisher
United States: National Acad Sciences
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Scope and Contents
Contents
To determine whether genetic variation within the MHC locus influences the risk of developing systemic juvenile idiopathic arthritis (sJIA), we examined a dense set of MHC region single nucleotide polymorphisms, classic HLA alleles, and the individual amino acids of HLA molecules in nine independent sJIA case-control populations. Association testin...
Alternative Titles
Full title
HLA-DRB111 and variants of the MHC class II locus are strong risk factors for systemic juvenile idiopathic arthritis
Authors, Artists and Contributors
Author / Creator
Remmers, Elaine F.
Tachmazidou, Ioanna
Grom, Alexei
Foell, Dirk
Haas, Johannes-Peter
Martini, Alberto
Gattorno, Marco
Özen, Seza
Prahalad, Sampath
Zeft, Andrew S.
Bohnsack, John F.
Mellins, Elizabeth D.
Ilowite, Norman T.
Russo, Ricardo
Len, Claudio
Hilario, Maria Odete E.
Oliveira, Sheila
Yeung, Rae S. M.
Rosenberg, Alan
Wedderburn, Lucy R.
Anton, Jordi
Schwarz, Tobias
Hinks, Anne
Bilginer, Yelda
Park, Jane
Cobb, Joanna
Satorius, Colleen L.
Han, Buhm
Baskin, Elizabeth
Signa, Sara
Duerr, Richard H.
Achkar, J. P.
Kamboh, M. Ilyas
Kaufman, Kenneth M.
Kottyan, Leah C.
Pinto, Dalila
Scherer, Stephen W.
Alarcón-Riquelme, Marta E.
Docampo, Elisa
Estivill, Xavier
Gül, Ahmet
de Bakker, Paul I. W.
Raychaudhuri, Soumya
Langefeld, Carl D.
Thompson, Susan
Zeggini, Eleftheria
Thomson, Wendy
Kastner, Daniel L.
Woo, Patricia
Achkar, J. P.
Alarcón-Riquelme, Marta E.
Allen, Roger
Anton, Jordi
Baskin, Elizabeth
Berg, Stefan
Bica, Bianca
Bilginer, Yelda
Bohnsack, John F.
Cavalcanti, Andre
Chaitow, Jeffrey
Cobb, Joanna
Cuttica, Rubin
de Bakker, Paul I. W.
Docampo, Elisa
Duerr, Richard
Ellis, Justine
Estivill, Xavier
Finkel, Terri H.
Foell, Dirk
Gattorno, Marco
Grom, Alexei
Gül, Ahmet
Haas, Johannes-Peter
Hakonarson, Hakon
Han, Buhm
Hilario, Maria Odete E.
Hinks, Anne
Ilowite, Norman T.
Kamboh, M. Ilyas
Kaufman, Kenneth
Kottyan, Leah C.
Langefeld, Carl
Len, Claudio
Martini, Alberto
Mellins, Elizabeth D.
Minden, Kirstin
Murray, Kevin
Oliveira, Sheila
Ombrello, Michael J.
Ozen, Seza
Park, Jane
Pinto, Dalila
Prahalad, Sampath
Quartier, Pierre
Raychaudhuri, Soumya
Rosenberg, Alan
Russo, Ricardo
Satorius, Colleen
Scherer, Stephen W.
Childhood Arthritis Prospective Study (CAPS) Group
British Society of Pediatric and Adolescent Rheumatology (BSPAR) Study Group
Randomized Placebo Phase Study of Rilonacept in sJIA (RAPPORT) Investigators
the International Childhood Arthritis Genetics (INCHARGE) Consortium
Sparks-Childhood Arthritis Response to Medication Study (CHARMS) Group
Biologically Based Outcome Predictors in JIA (BBOP) Group
International Childhood Arthritis Genetics (INCHARGE) Consortium
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pnas_primary_112_52_15970
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_112_52_15970
Other Identifiers
ISSN
0027-8424,1091-6490
E-ISSN
1091-6490
DOI
10.1073/pnas.1520779112
