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Quantitative proteomics identify DAB2 as a cardiac developmental regulator that inhibits WNT/β-caten...

Quantitative proteomics identify DAB2 as a cardiac developmental regulator that inhibits WNT/β-caten...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_113_4_1002

Quantitative proteomics identify DAB2 as a cardiac developmental regulator that inhibits WNT/β-catenin signaling

About this item

Full title

Quantitative proteomics identify DAB2 as a cardiac developmental regulator that inhibits WNT/β-catenin signaling

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2016-01, Vol.113 (4), p.1002-1007

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

To reveal the molecular mechanisms involved in cardiac lineage determination and differentiation, we quantified the proteome of human embryonic stem cells (hESCs), cardiac progenitor cells (CPCs), and cardiomyocytes during a time course of directed differentiation by label-free quantitative proteomics. This approach correctly identified known stage...

Alternative Titles

Full title

Quantitative proteomics identify DAB2 as a cardiac developmental regulator that inhibits WNT/β-catenin signaling

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pnas_primary_113_4_1002

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_113_4_1002

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1523930113

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