A Nondenaturing Zwitterionic Detergent for Membrane Biochemistry: Design and Synthesis
A Nondenaturing Zwitterionic Detergent for Membrane Biochemistry: Design and Synthesis
About this item
Full title
Author / Creator
Publisher
United States: National Academy of Sciences of the United States of America
Journal title
Language
English
Formats
Publication information
Publisher
United States: National Academy of Sciences of the United States of America
Subjects
More information
Scope and Contents
Contents
The synthesis and evaluation of a new detergent that is a zwitterionic derivative of cholic acid is presented. This detergent combines the useful properties of both the sulfobetaine-type detergents and the bile salt anions. The new detergent proved to be effective at solubilizing membrane proteins in a nondenatured state.
Alternative Titles
Full title
A Nondenaturing Zwitterionic Detergent for Membrane Biochemistry: Design and Synthesis
Authors, Artists and Contributors
Author / Creator
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Primary Identifiers
Record Identifier
TN_cdi_pnas_primary_77_11_6368
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_77_11_6368
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.77.11.6368
