Thiostrepton Inhibits the Turnover but Not the GTPase of Elongation Factor G on the Ribosome
Thiostrepton Inhibits the Turnover but Not the GTPase of Elongation Factor G on the Ribosome
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Publisher
United States: National Academy of Sciences of the United States of America
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Language
English
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United States: National Academy of Sciences of the United States of America
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Contents
The region around position 1067 in domain II of 23S rRNA frequently is referred to as the GTPase center of the ribosome. The notion is based on the observation that the binding of the antibiotic thiostrepton to this region inhibited GTP hydrolysis by elongation factor G (EF-G) on the ribosome at the conditions of multiple turnover. In the present w...
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Full title
Thiostrepton Inhibits the Turnover but Not the GTPase of Elongation Factor G on the Ribosome
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TN_cdi_pnas_primary_96_17_9586_fulltext
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_96_17_9586_fulltext
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.96.17.9586
