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Investigating Stem Cells in Human Colon by Using Methylation Patterns

Investigating Stem Cells in Human Colon by Using Methylation Patterns

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_98_19_10839

Investigating Stem Cells in Human Colon by Using Methylation Patterns

About this item

Full title

Investigating Stem Cells in Human Colon by Using Methylation Patterns

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2001-09, Vol.98 (19), p.10839-10844

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

The stem cells that maintain human colon crypts are poorly characterized. To better determine stem cell numbers and how they divide, epigenetic patterns were used as cell fate markers. Methylation exhibits somatic inheritance and random changes that potentially record lifelong stem cell division histories as binary strings or tags in adjacent CpG s...

Alternative Titles

Full title

Investigating Stem Cells in Human Colon by Using Methylation Patterns

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pnas_primary_98_19_10839

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_98_19_10839

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.191225998

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