Investigating Stem Cells in Human Colon by Using Methylation Patterns
Investigating Stem Cells in Human Colon by Using Methylation Patterns
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Contents
The stem cells that maintain human colon crypts are poorly characterized. To better determine stem cell numbers and how they divide, epigenetic patterns were used as cell fate markers. Methylation exhibits somatic inheritance and random changes that potentially record lifelong stem cell division histories as binary strings or tags in adjacent CpG s...
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Full title
Investigating Stem Cells in Human Colon by Using Methylation Patterns
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TN_cdi_pnas_primary_98_19_10839
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_98_19_10839
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.191225998