Induction of Pre-B Cell Proliferation after de novo Synthesis of the Pre-B Cell Receptor
Induction of Pre-B Cell Proliferation after de novo Synthesis of the Pre-B Cell Receptor
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Publisher
United States: National Academy of Sciences
Journal title
Language
English
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Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
The assembly of a pre-B cell receptor (pre-BCR) composed of an Ig μ heavy chain (μH-chain), the surrogate light (SL) chain, and the Igα/β dimer is critical for late pro-B cells to advance to the pre-B cell stage. By using a transgenic mouse model, in which μH-chain synthesis is solely driven by a tetracycline-controlled transactivator, we show that...
Alternative Titles
Full title
Induction of Pre-B Cell Proliferation after de novo Synthesis of the Pre-B Cell Receptor
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Record Identifier
TN_cdi_pnas_primary_98_4_1745
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_98_4_1745
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.041492098
