Isolation of a Diterpenoid Substance with Potent Neuroprotective Activity from Fetal Calf Serum
Isolation of a Diterpenoid Substance with Potent Neuroprotective Activity from Fetal Calf Serum
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Author / Creator
Kume, Toshiaki , Asai, Naoki , Nishikawa, Hiroyuki , Mano, Nariyasu , Terauchi, Taro , Taguchi, Ryota , Shirakawa, Hisashi , Osakada, Fumitaka , Mori, Hiroki , Asakawa, Naoki , Yonaga, Masahiro , Nishizawa, Yukio , Sugimoto, Hachiro , Shimohama, Shun , Katsuki, Hiroshi , Kaneko, Shuji and Akaike, Akinori
Publisher
United States: National Academy of Sciences
Journal title
Language
English
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Publication information
Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
Excess activation of glutamate receptors and production of free radicals including nitric oxide may result in severe and irreversible damage to the mammalian central nervous system (CNS), but endogenous defense systems that protect neurons from these insults are poorly understood. Here, we purified and isolated a neuroprotective substance, which ha...
Alternative Titles
Full title
Isolation of a Diterpenoid Substance with Potent Neuroprotective Activity from Fetal Calf Serum
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Primary Identifiers
Record Identifier
TN_cdi_pnas_primary_99_5_3288_fulltext
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_99_5_3288_fulltext
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.052693999
