Mitosis is not a key target of microtubule agents in patient tumors
Mitosis is not a key target of microtubule agents in patient tumors
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
In this Perspective, the clinical disappointment of mitosis-specific agents is explained in the context of the mechanism of action of microtubule-targeting agents. The authors propose a new paradigm for the anticancer activity of microtubule-targeting agents and suggest that mitosis-specific inhibitors will not result in significant clinical impact...
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Full title
Mitosis is not a key target of microtubule agents in patient tumors
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TN_cdi_proquest_journals_1029875171
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1029875171
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ISSN
1759-4774
E-ISSN
1759-4782
DOI
10.1038/nrclinonc.2010.228
