Pharmacokinetics and dosimetry of iodine-123 labelled PE2I in humans, a radioligand for dopamine tra...
Pharmacokinetics and dosimetry of iodine-123 labelled PE2I in humans, a radioligand for dopamine transporter imaging
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Kuikka, J T , Baulieu, J L , Hiltunen, J , Halldin, C , Bergström, K A , Farde, L , Emond, P , Chalon, S , Yu, M , Nikula, T , Laitinen, T , Karhu, J , Tupala, E , Hallikainen, T , Kolehmainen, V , Mauclaire, L , Maziere, B , Tiihonen, J and Guilloteau, D
Publisher
Germany: Springer Nature B.V
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English
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Publisher
Germany: Springer Nature B.V
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Contents
The iodine-123 labelled selective ligand N-(3-iodoprop-2E-enyl)-2-beta-carbomethoxy-3beta-(4-methylphenyl) nortropane ([123I]PE2I) was evaluated as a probe for in vivo dopamine transporter imaging in the human brain. Six healthy subjects were imaged with a high-resolution single-photon emission tomography scanner. Striatal radioactivity peaked at 1...
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Full title
Pharmacokinetics and dosimetry of iodine-123 labelled PE2I in humans, a radioligand for dopamine transporter imaging
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TN_cdi_proquest_journals_1038771186
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1038771186
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ISSN
0340-6997,1619-7070
E-ISSN
1619-7089
DOI
10.1007/s002590050254
