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Basal Forebrain Cholinergic Immunolesion by 192IgG-Saporin: Evidence for a Presynaptic Location of S...

Basal Forebrain Cholinergic Immunolesion by 192IgG-Saporin: Evidence for a Presynaptic Location of S...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1094507330

Basal Forebrain Cholinergic Immunolesion by 192IgG-Saporin: Evidence for a Presynaptic Location of Subpopulations of [alpha]2-and [beta]-Adrenergic as Well as 5-HT2A Receptors on Cortical Cholinergic Terminals

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Full title

Basal Forebrain Cholinergic Immunolesion by 192IgG-Saporin: Evidence for a Presynaptic Location of Subpopulations of [alpha]2-and [beta]-Adrenergic as Well as 5-HT2A Receptors on Cortical Cholinergic Terminals

Publisher

New York: Springer Nature B.V

Journal title

Neurochemical research, 1997-08, Vol.22 (8), p.957

Language

English

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Publication information

Publisher

New York: Springer Nature B.V

Subjects

Subjects and topics

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Scope and Contents

Contents

To study whether the changes in cortical noradrenergic and serotonergic mechanisms observed in patients with Alzheimer's disease are the consequence of reduced cortical cholinergic activity, a novel cholinergic immunotoxin (conjugate of the monoclonal antibody 192IgG against the low-affinity nerve growth factor receptor with the cytotoxic protein s...

Alternative Titles

Full title

Basal Forebrain Cholinergic Immunolesion by 192IgG-Saporin: Evidence for a Presynaptic Location of Subpopulations of [alpha]2-and [beta]-Adrenergic as Well as 5-HT2A Receptors on Cortical Cholinergic Terminals

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Record Identifier

TN_cdi_proquest_journals_1094507330

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1094507330

Other Identifiers

ISSN

0364-3190

E-ISSN

1573-6903

DOI

10.1023/A:1022418708293

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