Local delivery of rolipram, a phosphodiesterase-4-specific inhibitor, augments bone morphogenetic pr...
Local delivery of rolipram, a phosphodiesterase-4-specific inhibitor, augments bone morphogenetic protein-induced bone formation
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Japan: Japan : Springer Japan
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Language
English
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Japan: Japan : Springer Japan
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Recombinant human bone morphogenetic protein (rhBMP) is a promising therapeutic cytokine for the induction of bone formation, but a weak response in humans remains a major hurdle in its therapeutic application. We have previously reported an rhBMP-2-induced increase in the bone mass of mice receiving systemic rolipram, a specific inhibitor of phosp...
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Full title
Local delivery of rolipram, a phosphodiesterase-4-specific inhibitor, augments bone morphogenetic protein-induced bone formation
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TN_cdi_proquest_journals_1113446571
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1113446571
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ISSN
0914-8779
E-ISSN
1435-5604
DOI
10.1007/s00774-009-0103-5
