Randomized Trial of Tocilizumab in Systemic Juvenile Idiopathic Arthritis
Randomized Trial of Tocilizumab in Systemic Juvenile Idiopathic Arthritis
About this item
Full title
Author / Creator
De Benedetti, Fabrizio , Brunner, Hermine I , Ruperto, Nicolino , Kenwright, Andrew , Wright, Stephen , Calvo, Inmaculada , Cuttica, Ruben , Ravelli, Angelo , Schneider, Rayfel , Woo, Patricia , Wouters, Carine , Xavier, Ricardo , Zemel, Lawrence , Baildam, Eileen , Burgos-Vargas, Ruben , Dolezalova, Pavla , Garay, Stella M , Merino, Rosa , Joos, Rik , Grom, Alexei , Wulffraat, Nico , Zuber, Zbigniew , Zulian, Francesco , Lovell, Daniel , Martini, Alberto , PRCSG and PRINTO
Publisher
Waltham, MA: Massachusetts Medical Society
Journal title
Language
English
Formats
Publication information
Publisher
Waltham, MA: Massachusetts Medical Society
Subjects
More information
Scope and Contents
Contents
In a randomized trial involving children with severe systemic juvenile idiopathic arthritis, the anti–interleukin-6 receptor antibody tocilizumab was effective (response rate, 85% with tocilizumab vs. 24% with placebo). Adverse events included serious infections and neutropenia.
Systemic juvenile idiopathic arthritis (JIA) is characterized by ch...
Alternative Titles
Full title
Randomized Trial of Tocilizumab in Systemic Juvenile Idiopathic Arthritis
Authors, Artists and Contributors
Author / Creator
Brunner, Hermine I
Ruperto, Nicolino
Kenwright, Andrew
Wright, Stephen
Calvo, Inmaculada
Cuttica, Ruben
Ravelli, Angelo
Schneider, Rayfel
Woo, Patricia
Wouters, Carine
Xavier, Ricardo
Zemel, Lawrence
Baildam, Eileen
Burgos-Vargas, Ruben
Dolezalova, Pavla
Garay, Stella M
Merino, Rosa
Joos, Rik
Grom, Alexei
Wulffraat, Nico
Zuber, Zbigniew
Zulian, Francesco
Lovell, Daniel
Martini, Alberto
PRCSG
PRINTO
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_1242080091
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1242080091
Other Identifiers
ISSN
0028-4793
E-ISSN
1533-4406
DOI
10.1056/NEJMoa1112802
