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Involvement of the P2X7 Purinergic Receptor and c-Jun N-Terminal and Extracellular Signal-Regulated...

Involvement of the P2X7 Purinergic Receptor and c-Jun N-Terminal and Extracellular Signal-Regulated...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1312326813

Involvement of the P2X7 Purinergic Receptor and c-Jun N-Terminal and Extracellular Signal-Regulated Kinases in Cyclooxygenase-2 and Prostaglandin E2 Induction by LL-37

About this item

Full title

Involvement of the P2X7 Purinergic Receptor and c-Jun N-Terminal and Extracellular Signal-Regulated Kinases in Cyclooxygenase-2 and Prostaglandin E2 Induction by LL-37

Publisher

Basel, Switzerland: S. Karger AG

Journal title

Journal of innate immunity, 2013-01, Vol.5 (1), p.72-83

Language

English

Formats

Publication information

Publisher

Basel, Switzerland: S. Karger AG

More information

Scope and Contents

Contents

Periodontal disease is caused by microorganisms and host-derived inflammation involving increased cyclooxygenase-2 (COX-2) expression and prostaglandin E 2 (PGE 2 ) production. We previously demonstrated that human β-defensin-3 induces COX-2 and PGE 2 in human gingival fibroblasts (HGFs). We, therefore, aimed to examine the inducible effects of LL-...

Alternative Titles

Full title

Involvement of the P2X7 Purinergic Receptor and c-Jun N-Terminal and Extracellular Signal-Regulated Kinases in Cyclooxygenase-2 and Prostaglandin E2 Induction by LL-37

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_1312326813

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1312326813

Other Identifiers

ISSN

1662-811X

E-ISSN

1662-8128

DOI

10.1159/000342928

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