MUS81 Generates a Subset of MLH1-MLH3-Independent Crossovers in Mammalian Meiosis: e1000186
MUS81 Generates a Subset of MLH1-MLH3-Independent Crossovers in Mammalian Meiosis: e1000186
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San Francisco: Public Library of Science
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English
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San Francisco: Public Library of Science
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Two eukaryotic pathways for processing double-strand breaks (DSBs) as crossovers have been described, one dependent on the MutL homologs Mlh1 and Mlh3, and the other on the structure-specific endonuclease Mus81. Mammalian MUS81 has been implicated in maintenance of genomic stability in somatic cells; however, little is known about its role during m...
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Full title
MUS81 Generates a Subset of MLH1-MLH3-Independent Crossovers in Mammalian Meiosis: e1000186
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TN_cdi_proquest_journals_1313494441
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1313494441
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ISSN
1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1000186
