Efficacy and safety of a microsomal triglyceride transfer protein inhibitor in patients with homozyg...
Efficacy and safety of a microsomal triglyceride transfer protein inhibitor in patients with homozygous familial hypercholesterolaemia: a single-arm, open-label, phase 3 study
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Author / Creator
Cuchel, Marina, Dr , Meagher, Emma A, MD , du Toit Theron, Hendrik, Prof , Blom, Dirk J, PhD , Marais, A David, Prof , Hegele, Robert A, Prof , Averna, Maurizio R, Prof , Sirtori, Cesare R, Prof , Shah, Prediman K, Prof , Gaudet, Daniel, MD , Stefanutti, Claudia, MD , Vigna, Giovanni B, MD , Du Plessis, Anna ME, MMed , Propert, Kathleen J, Prof , Sasiela, William J, PhD , Bloedon, LeAnne T, MS , Rader, Daniel J, Prof , for the Phase 3 HoFH Lomitapide Study investigators and Phase 3 HoFH Lomitapide Study investigators
Publisher
Kidlington: Elsevier Ltd
Journal title
Language
English
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Publication information
Publisher
Kidlington: Elsevier Ltd
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Scope and Contents
Contents
Summary Background Patients with homozygous familial hypercholesterolaemia respond inadequately to existing drugs. We aimed to assess the efficacy and safety of the microsomal triglyceride transfer protein inhibitor lomitapide in adults with this disease. Methods We did a single-arm, open-label, phase 3 study of lomitapide for treatment of patients...
Alternative Titles
Full title
Efficacy and safety of a microsomal triglyceride transfer protein inhibitor in patients with homozygous familial hypercholesterolaemia: a single-arm, open-label, phase 3 study
Authors, Artists and Contributors
Author / Creator
Meagher, Emma A, MD
du Toit Theron, Hendrik, Prof
Blom, Dirk J, PhD
Marais, A David, Prof
Hegele, Robert A, Prof
Averna, Maurizio R, Prof
Sirtori, Cesare R, Prof
Shah, Prediman K, Prof
Gaudet, Daniel, MD
Stefanutti, Claudia, MD
Vigna, Giovanni B, MD
Du Plessis, Anna ME, MMed
Propert, Kathleen J, Prof
Sasiela, William J, PhD
Bloedon, LeAnne T, MS
Rader, Daniel J, Prof
for the Phase 3 HoFH Lomitapide Study investigators
Phase 3 HoFH Lomitapide Study investigators
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Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_1315208743
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1315208743
Other Identifiers
ISSN
0140-6736
E-ISSN
1474-547X
DOI
10.1016/S0140-6736(12)61731-0
