Astrocyte pathology and the absence of non-cell autonomy in an induced pluripotent stem cell model o...
Astrocyte pathology and the absence of non-cell autonomy in an induced pluripotent stem cell model of TDP-43 proteinopathy
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Author / Creator
Serio, Andrea , Bilican, Bilada , Barmada, Sami J. , Ando, Dale Michael , Zhao, Chen , Siller, Rick , Burr, Karen , Haghi, Ghazal , Story, David , Nishimura, Agnes Lumi , Carrasco, Monica A. , Phatnani, Hemali P. , Shum, Carole , Wilmut, Ian , Maniatis, Tom , Shaw, Christopher E. , Finkbeiner, Steven and Chandran, Siddharthan
Publisher
United States: National Academy of Sciences
Journal title
Language
English
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Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
Glial proliferation and activation are associated with disease progression in amyotrophic lateral sclerosis (ALS) and frontotemporal lobar dementia. In this study, we describe a unique platform to address the question of cell autonomy in tran s active response DNA-binding protein (TDP-43) proteinopathies. We generated functional astroglia from huma...
Alternative Titles
Full title
Astrocyte pathology and the absence of non-cell autonomy in an induced pluripotent stem cell model of TDP-43 proteinopathy
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Record Identifier
TN_cdi_proquest_journals_1318855747
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1318855747
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1300398110
